(-)-N,N-二苯甲基-D-酒石二酰胺合成路线 （共 4 条）
反应条件
potassium carbonate in methanol 8 h; Heating;
参考文献
Chen, Wansuo; Liu, Yanzhu; Chen, Zhirong
European Journal of Organic Chemistry, 2005 , # 8 p. 1665 - 1668
反应条件
N-3,5-dimethylphenylcarbamoyl-derivatized cyclofructan-6 column in n-heptane; isopropyl alcohol; trifluoroacetic acid T=20°C; Resolution of racemate;
参考文献
Sun, Ping; Wang, Chunlei; Breitbach, Zachary S.; Zhang, Ying; Armstrong, Daniel W.
Analytical Chemistry, 2009 , vol. 81, # 24 p. 10215 - 10226
反应条件
chiral stationary phase including dimethylphenylcarbamate-functionalized CF6 in n-heptane; trifluoroacetic acid T=20°C; Purification / work up;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 55 ;
反应条件
1: 1.69 g / Et3N / CH2Cl2 / 0.5 h / 20 °C 2: 83 percent / H2SO4 / ethanol / 4 h / Heating View Scheme
参考文献
Pecanha, Emerson P.; Figueiredo, Luciana J.O.; Brindeiro, Rodrigo M.; Tanuri, Amilcar; Calazans, Alexandre R.; Antunes
Farmaco, 2003 , vol. 58, # 2 p. 149 - 157
