N-(5-溴-2-氯吡啶-3-基)苯磺酰胺合成路线 （共 4 条）
反应条件
pyridine in dichloromethane T=20°C; 18.0833 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/39140 A1, 2009 ;
Location in patent: Page/Page column 49-50 ;
WO 2009/039140 A1
反应条件
pyridine in dichloromethane T=20°C; 72 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/55418 A1, 2009 ;
Location in patent: Page/Page column 53-54 ;
WO 2009/055418 A1
反应条件
1: trichlorophosphate / N,N-dimethyl-formamide / 2 h / Reflux 2: ethanol; tin(ll) chloride / 1 h / Reflux 3: pyridine / pyridine / 0.67 h / 0 - 20 °C View Scheme
参考文献
CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD.
Patent: US2012/238587 A1, 2012 ;
US 20120238587 A1
反应条件
1: ethanol; tin(ll) chloride / 1 h / Reflux 2: pyridine / pyridine / 0.67 h / 0 - 20 °C View Scheme
参考文献
CHEMIZON, A DIVISION OF OPTOMAGIC CO., LTD.
Patent: US2012/238587 A1, 2012 ;
US 20120238587 A1
