5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-3-吡啶磺酰胺合成路线 （共 2 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in 1,4-dioxane T=120°C; 0.666667 h; microwave irradiation;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/150827 A1, 2008 ;
Location in patent: Page/Page column 59 ;
WO 2008/150827 A1
反应条件
1.1: phosphorus pentachloride; trichlorophosphate / 4 h / Reflux 1.2: 14 h / Reflux 1.3: 0 - 20 °C 2.1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / 1,4-dioxane / 0.75 h / 120 °C / Inert atmosphere; Microwave irradiation View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; JOHNSON, James A.; LLOYD, John; FINLAY, Heather; JIANG, Ji; NEELS, James; DHONDI, Naveen Kumar; GUNAGA, Prashantha; BANERJEE, Abhisek; ADISECHAN, Ashokkumar
Patent: WO2011/28741 A1, 2011 ;
WO 2011/028741 A1
