2’-单脱羟基-2’-氯更昔洛韦合成路线 （共 3 条）
反应条件
1: H2, conc. HCl / 10percent Pd/C / methanol; H2O / 96 h / 50 Torr 2: conc. NH4OH / methanol / 18 h / Ambient temperature View Scheme
参考文献
Martin; McGee; Jeffrey; Hobbs; Smee; Matthews; Verheyden
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1384 - 1389
反应条件
1: (NH4)2SO4 / 24 h / Heating 2: 1) Bu4NF / 1) THF, benzene, reflux, 2) reflux, 30h View Scheme
参考文献
Zakerinia; Davary; Hakimelahi
Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 912 - 915
反应条件
tetrabutyl ammonium fluoride 1) THF, benzene, reflux, 2) reflux, 30h; Yield given. Multistep reaction;
参考文献
Zakerinia; Davary; Hakimelahi
Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 912 - 915
