3-[3-(4-甲氧基苯基)-1-苯基-1H-4-吡唑]-丙烯酸合成路线 （共 7 条）
反应条件
pyridine 0.0833333 h; microwave irradiation;
参考文献
Chornous, Vitaliy O.; Bratenko, Mykhaylo K.; Vovk, Mykhaylo V.
Synthetic Communications, 2004 , vol. 34, # 1 p. 79 - 83
反应条件
piperidine in pyridine T=95 - 100°C;
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: 92.5 percent / POCl3 2: 82.8 percent / piperidine 3: 77.8 percent / NaOH / methanol; H2O / 2 h / Heating 4: pyridine / 0.5 h / 100 °C View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: 82.8 percent / piperidine 2: 77.8 percent / NaOH / methanol; H2O / 2 h / Heating 3: pyridine / 0.5 h / 100 °C View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
in pyridine T=100°C; 0.5 h; Yield given;
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: sodium acetate / ethanol / 3 h / 50 - 60 °C 2: trichlorophosphate / 50 - 60 °C / Cooling 3: piperidine; pyridine / 5 h / 40 - 50 °C View Scheme
参考文献
Li, Xi; Liu, Jia-Lin; Yang, Xian-Hui; Lu, Xiang; Zhao, Ting-Ting; Gong, Hai-Bin; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 14 p. 4430 - 4436
反应条件
1: sodium acetate / ethanol / 3 h / 50 - 60 °C 2: trichlorophosphate / 50 - 60 °C / Cooling 3: piperidine; pyridine / 5 h / 40 - 50 °C View Scheme
参考文献
Li, Xi; Liu, Jia-Lin; Yang, Xian-Hui; Lu, Xiang; Zhao, Ting-Ting; Gong, Hai-Bin; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 14 p. 4430 - 4436
