N-[3-(氨基甲基)苄基]氨基甲酸叔丁酯合成路线 （共 12 条）
反应条件
in chloroform T=0 - 20°C;
参考文献
Dardonville, Christophe; Fernandez-Fernandez, Cristina; Gibbons, Sarah-Louise; Ryan, Gary J.; Jagerovic, Nadine; Gabilondo, Ane M.; Meana, J. Javier; Callado, Luis F.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6570 - 6580
反应条件
triethylamine in methanol; dichloromethane
参考文献
Glaxo Wellcome Inc.
Patent: US6090846 A1, 2000 ;
参考文献
US5914319 A1, ;
US 5914319 A
反应条件
hydrogenchloride in diethyl ether 0.5 h;
参考文献
Gross, Ralf; Duerner, Gerd; Goebel, Michael W.
Liebigs Annalen der Chemie, 1994 , # 1 p. 49 - 58
反应条件
sodium tetrahydroborate in tetrahydrofuran T=35°C; 24 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
反应条件
1: aq. NaN3 / tetrahydrofuran / 18 h / 20 °C 2: H2 / 5 percent Pd/C / tetrahydrofuran / 2 h / 20 °C / 2327.17 Torr 3: tetrahydrofuran / 2 h / 20 °C 4: NaBH4; aq. CoCl2 / tetrahydrofuran / 24 h / 35 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
反应条件
1: H2 / 5 percent Pd/C / tetrahydrofuran / 2 h / 20 °C / 2327.17 Torr 2: tetrahydrofuran / 2 h / 20 °C 3: NaBH4; aq. CoCl2 / tetrahydrofuran / 24 h / 35 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
反应条件
1: tetrahydrofuran / 2 h / 20 °C 2: NaBH4; aq. CoCl2 / tetrahydrofuran / 24 h / 35 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
反应条件
1: tetrahydrofuran / 2 h / 20 °C 2: NaBH4; aq. CoCl2 / tetrahydrofuran / 24 h / 35 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3477 - 3482
反应条件
1: 96 percent / 0.5M aq. NaOH / dioxane / 15 h / Ambient temperature 2: 63 percent / HCl / diethyl ether / 0.5 h View Scheme
参考文献
Liebigs Annalen der Chemie, , # 1 p. 49 - 58
