(R)-八氢-1H-吲哚-2-羧酸合成路线 (共 8 条)
反应条件
1: H2 / Rh/C / acetic acid 2: aq. 15percent HCl / 4 h / Heating 3: 96.6 percent / 2N NaOH / H2O / 3 h / 5 °C 5: HCl / H2O / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 992 - 998
反应条件
hydrogenchloride in water 4 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 992 - 998
反应条件
1: 96.6 percent / 2N NaOH / H2O / 3 h / 5 °C 3: HCl / H2O / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 992 - 998
反应条件
1: aq. 15percent HCl / 4 h / Heating 2: 96.6 percent / 2N NaOH / H2O / 3 h / 5 °C 4: HCl / H2O / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 992 - 998
反应条件
2: HCl / H2O / 4 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 992 - 998
参考文献
WO2004/99138 A2, ;
Page 7; 22; scheme ;
反应条件
2: Ba(OH)2.8H2O / 2 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 48 p. 5339 - 5342
反应条件
barium dihydroxide 2 h; Heating; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 24, # 48 p. 5339 - 5342