hydrogen; palladium on activated charcoal in ethanol; acetic acid Ambient temperature;

1: 87 percent / H2 / 10percent Pd/C / ethanol; acetic acid / Ambient temperature 2: N,N-diisopropylethylamine / tetrahydrofuran / 0.75 h / -78 °C 3: N,N-diisopropylethylamine / tetrahydrofuran / -78 °C / -78 deg C, 2 h; r.t., 1 h 4: 30percent H2O2 / CH2Cl2 / 1 h / 0 °C 5: 83 percent / toluene / 24 h / 40 - 60 °C View Scheme