sodium hydroxide in water; xylene T=15 - 25°C; 0.666667 h; Product distribution / selectivity;

1: (Z)-ethyl 2-(ethoxymethylene)-4,4-difluoro-3-oxobutanoate With hydrazine hydrate in toluene T=15 - 20°C; 2.5 h; 2: dimethyl sulfate With anhydrous tetramethylammonium chloride; sodium hydroxide in water; toluene T=20°C; pH=10.5 - 12; 4 h; Product distribution / selectivity;

1: With sodium hydroxide in water; xylene T=15 - 25°C; 0.666667 h; 2: With sodium hydroxide; water in xylene T=65°C; 0.75 h; 3: With hydrogenchloride; water in xylene T=95°C; 0.166667 h; Product distribution / selectivity;

1: With sodium hydroxide in water; xylene T=15 - 25°C; 0.666667 h; 2: With sodium hydroxide; water in xylene T=65°C; 0.75 h; 3: With hydrogenchloride; water in xylene T=95°C; 0.166667 h; Product distribution / selectivity;