(2-溴-1,1-二氟乙基)苯合成路线 （共 5 条）
反应条件
N-bromosuccinmide; triethylamine tris(hydrogen fluoride) in dichloromethane T=25°C;
参考文献
Schlosser, Manfred; Bruegger, Nadia; Schmidt, Werner; Amrhein, Nikolaus
Tetrahedron, 2004 , vol. 60, # 35 p. 7731 - 7742
反应条件
1: 81 percent / t-BuOK / tetrahydrofuran / 2 h / 25 °C 2: 91 percent / Et3N*3HF; N-bromosuccinimide / CH2Cl2 / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 35 p. 7731 - 7742
反应条件
4,4'-diaminostilbene-2,2'-disulfonic acid in benzene T=65°C; 48 h;
参考文献
Buss,C.W.; Coe,P.L.; Tatlow,J.C.
Journal of Fluorine Chemistry, 1986 , vol. 34, p. 83
反应条件
1: 75 percent / t-BuOK / tetrahydrofuran / 5 h / 0 °C 2: 90 percent / triethylamine tris(hydrofluoride), N-bbromosuccinimide / CH2Cl2 / 2 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 46, # 12 p. 4255 - 4260
反应条件
tri-n-butyl-tin hydride T=60°C; 2 h;
参考文献
Suga, Hiroaki; Hamatani, Takeshi; Guggisberg, Yves; Schlosser, Manfred
Tetrahedron, 1990 , vol. 46, # 12 p. 4255 - 4260
