1-苄基-4-苯基-1,2,3-噻唑合成路线 （共 52 条）
反应条件
Cu2(OH)3OAc*H2O in acetonitrile
T=100°C; 0.166667 h; Microwave irradiation;
参考文献
Buckley, Benjamin R.; Dann, Sandra E.; Harris, Daniel P.; Heaney, Harry; Stubbs, Emma C.
Chemical Communications, 2010 , vol. 46, # 13 p. 2274 - 2276
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; tetrabutylammomium bromide; potassium carbonate in methanol; water
T=20 - 150°C; Suzuki-Miyaura Coupling; 0.666667 h; Microwave irradiation; Reagent/catalystSolventTimeTemperature;
参考文献
Kim, Taejung; Song, Jung Ho; Jeong, Kyu Hyuk; Lee, Seokjoon; Ham, Jungyeob
European Journal of Organic Chemistry, 2013 , # 19 p. 3992 - 3996
反应条件
acetic acid in cyclohexane
T=25°C; 0.0833333 h;
参考文献
Shao, Changwei; Wang, Xinyan; Xu, Jimin; Zhao, Jichen; Zhang, Qun; Hu, Yuefei
Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 7002 - 7005
反应条件
acetic acid in cyclohexane
T=20°C; 0.0833333 h;
参考文献
Shao, Changwei; Wang, Xinyan; Zhang, Qun; Luo, Sheng; Zhao, Jichen; Hu, Yuefei
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6832 - 6836
反应条件
imidazole-1-sulfonyl azide hydrochloride; CuSO4‵5H2O; ascorbic acid sodium salt; triethylamine in ethanol
T=20°C; Inert atmosphere;
参考文献
Smith, Neal M.; Greaves, Michelle J.; Jewell, Robert; Perry, Matthew W. D.; Stocks, Michael J.; Stonehouse, Jeffrey P.
Synlett, 2009 , # 9 p. 1391 - 1394
反应条件
1: With copper(l) iodide; N,N,N',N'',N''-pentamethyldiethylenetriamine in toluene
T=20°C; 48 h;
2: With water; Potassium sodium tartrate in toluene
Cooling; regioselective reaction;
参考文献
Zhou, Yuhan; Lecourt, Thomas; Micouin, Laurent
Angewandte Chemie - International Edition, 2010 , vol. 49, # 14 p. 2607 - 2610
反应条件
1: sodium azide / dimethyl sulfoxide / 1 h / 20 °C
2: C25H36CuI / 0.17 h / 20 °C / Neat (no solvent)
View Scheme
参考文献
Diez-Gonzalez, Silvia; Escudero-Adan, Eduardo C.; Benet-Buchholz, Jordi; Stevens, Edwin D.; Slawin, Alexandra M. Z.; Nolan, Steven P.
Dalton Transactions, 2010 , vol. 39, # 32 p. 7595 - 7606
反应条件
NiCl2((PPh3)P)2; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=60°C; Negishi Coupling;
参考文献
Stefani, Helio A.; Leal, Daiana M.; Manarin, Flavia
Tetrahedron Letters, 2012 , vol. 53, # 48 p. 6495 - 6499,5
反应条件
sodium azide; sodium hydrogencarbonate; iron(III) chloride; copper in water
2 h; Heating;
参考文献
Saha, Biswajit; Sharma, Sunil; Sawant, Devesh; Kundu, Bijoy
Synlett, 2007 , # 10 p. 1591 - 1594
反应条件
[(PhCCCu)2]n in acetonitrile
Microwave irradiation;
参考文献
Buckley, Benjamin R.; Dann, Sandra E.; Harris, Daniel P.; Heaney, Harry; Stubbs, Emma C.
Chemical Communications, 2010 , vol. 46, # 13 p. 2274 - 2276
