9-甲基-9H-咔唑-2-甲醛合成路线 （共 4 条）
反应条件
1: C13H10BrN With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; Inert atmosphere;
2: N,N-dimethyl-formamide T=0°C; 12 h; Inert atmosphere;
参考文献
Bu, Lingyu; Li, Yiping; Wang, Jianfeng; Sun, Mingxiao; Zheng, Meng; Liu, Wei; Xue, Shanfeng; Yang, Wenjun
Dyes and Pigments, 2013 , vol. 99, # 3 p. 833 - 838
反应条件
1.1: sodium hydroxide / water; dimethyl sulfoxide / 90 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C / |Inert atmosphere
2.2: 12 h / 0 °C / |Inert atmosphere
View Scheme
参考文献
Bu, Lingyu; Li, Yiping; Wang, Jianfeng; Sun, Mingxiao; Zheng, Meng; Liu, Wei; Xue, Shanfeng; Yang, Wenjun
Dyes and Pigments, 2013 , vol. 99, # 3 p. 833 - 838
反应条件
1: 75 percent / 10percent NaOH / ethanol / 4 h / Heating
2: 1) NaH / 1) DMF, r.t., 1 h, 2) r.t., 1 h
View Scheme
参考文献
Molina, Pedro; Fresneda, Pilar M.; Almendros, Pedro
Tetrahedron, 1993 , vol. 49, # 6 p. 1223 - 1236
反应条件
sodium hydride
1) DMF, r.t., 1 h, 2) r.t., 1 h; Yield given. Multistep reaction;
参考文献
Molina, Pedro; Fresneda, Pilar M.; Almendros, Pedro
Tetrahedron, 1993 , vol. 49, # 6 p. 1223 - 1236
