4-溴-3-二氟甲基-1-甲基吡唑合成路线 （共 7 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=3 - 20°C; Product distribution / selectivity;
参考文献
BASF SE
Patent: US2010/174094 A1, 2010 ;
Location in patent: Page/Page column 11-12 ;
反应条件
1: With triethylamine tris(hydrogen fluoride) T=160°C; P=750.075 Torr; 1 h; 2: With water; sodium hydroxide
参考文献
BASF SE
Patent: US2010/174094 A1, 2010 ;
Location in patent: Page/Page column 17 ;
反应条件
dppdmp; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis(benzonitrile)palladium(II) dichloride in N,N-dimethyl-formamide T=20 - 150°C; P=11251.1 Torr; Autoclave;
参考文献
BASF SE
Patent: US2010/174094 A1, 2010 ;
Location in patent: Page/Page column 19 ;
反应条件
triethylamine; triphenylphosphine; tris-triphenylphosphine palladium (II) chloride T=150°C; P=4500.45 - 5250.53 Torr; Product distribution / selectivity;
参考文献
EP2008996 A1, ;
Page/Page column 13 ;
反应条件
water; triethylamine; triphenylphosphine; tris(triphenylphosphonium)palladium(II)chloride in 1-methyl-pyrrolidin-2-one T=150°C; P=4500.45 - 5250.53 Torr; Product distribution / selectivity;
参考文献
EP2008996 A1, ;
Page/Page column 9; 14 ;
反应条件
dCypp; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis(benzonitrile)palladium(II) dichloride in N,N-dimethyl-formamide
T=130°C; P=11251.1 Torr; 16 h; Inert atmosphere; Product distribution / selectivity;
参考文献
BASF SE
Patent: US2010/174094 A1, 2010 ;
Location in patent: Page/Page column 11 ;
反应条件
dppdmp; 1,8-diazabicyclo[5.4.0]undec-7-ene; bis(benzonitrile)palladium(II) dichloride in N,N-dimethyl-formamide
T=20 - 150°C; P=11251.1 Torr; Autoclave;
参考文献
BASF SE
Patent: US2010/174094 A1, 2010 ;
Location in patent: Page/Page column 19 ;
