5-[(1E)-2-(3,5-二甲氧基苯基)乙烯基]-2-甲氧基苯酚合成路线 （共 9 条）
反应条件
triethanolamine; palladium diacetate T=100°C; Mizoroki-Heck reaction; 24 h; Inert atmosphere;
参考文献
Csuk, Rene; Albert, Sabrina; Siewert, Bianka; Schwarz, Stefan
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 669 - 678
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h;
参考文献
Gao, Mingzhang; Wang, Min; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5767 - 5772
反应条件
boron tribromide; isoascorbic acid in dichloromethane T=-78 - 20°C; Inert atmosphere;
参考文献
Lee, Hyun Suck; Lee, Byung Won; Kim, Mi Ran; Jun, Jong-Gab
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 4 p. 971 - 975
反应条件
1.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 1.2: tetrahydrofuran / 5 h / 20 °C 2.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 1.2: tetrahydrofuran / 5 h / 20 °C 2.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: 92 percent / triethylamine / dimethylformamide / 20 °C 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C 3.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: 90 percent / toluene / 14 h / Heating 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C 3.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 4 p. 323 - 327
反应条件
potassium carbonate in acetone 5 h; Heating;
参考文献
Gao, Mingzhang; Wang, Min; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5767 - 5772
