1: 24 percent / 1N aq. NaOH / methanol; acetonitrile / 0.5 h / Ambient temperature 2: 6.1 mg / H2 / 5percent Pd/C / methanol / 3 h / Ambient temperature 3: 39 percent / N,N-dicyclohexylcarbodimide / dioxane / 15 h 4: 60 percent / AlCl3 / CH2Cl2 / 2 h / Ambient temperature View Scheme

1: 24 percent / 1N aq. NaOH / methanol; acetonitrile / 0.5 h / Ambient temperature 2: 6.1 mg / H2 / 5percent Pd/C / methanol / 3 h / Ambient temperature 3: 39 percent / N,N-dicyclohexylcarbodimide / dioxane / 15 h View Scheme

Multi-step reaction with 6 steps 1: 76 percent / N,N-dicyclohexylcarbodiimide / dioxane / 20 h / Ambient temperature2: 5.2 percent / thallium(III) trinitrate / 18 h / 4 °C3: 38 percent / 90percent aq. AcOH, Zn / 1 h / Ambient temperature4: 78.4 percent / diethyl ether; methanol / 1 h / Ambient temperature5: 71.4 percent / AcOK, H2 / 5percent Pd/C / methanol / Ambient temperature6: 63 percent / N,N-dicyclohexylcarbodimide / dioxane / 4 h / Ambient temperature  

Multi-step reaction with 6 steps 1: 76 percent / N,N-dicyclohexylcarbodiimide / dioxane / 20 h / Ambient temperature2: 5.2 percent / thallium(III) trinitrate / 18 h / 4 °C3: 38 percent / 90percent aq. AcOH, Zn / 1 h / Ambient temperature4: 78.4 percent / diethyl ether; methanol / 1 h / Ambient temperature5: 71.4 percent / AcOK, H2 / 5percent Pd/C / methanol / Ambient temperature6: 63 percent / N,N-dicyclohexylcarbodimide / dioxane / 4 h / Ambient temperature  

Multi-step reaction with 3 steps 1: 78.4 percent / diethyl ether; methanol / 1 h / Ambient temperature2: 71.4 percent / AcOK, H2 / 5percent Pd/C / methanol / Ambient temperature3: 63 percent / N,N-dicyclohexylcarbodimide / dioxane / 4 h / Ambient temperature  

Multi-step reaction with 2 steps 1: 71.4 percent / AcOK, H2 / 5percent Pd/C / methanol / Ambient temperature2: 63 percent / N,N-dicyclohexylcarbodimide / dioxane / 4 h / Ambient temperature  

Multi-step reaction with 4 steps 1: 38 percent / 90percent aq. AcOH, Zn / 1 h / Ambient temperature2: 78.4 percent / diethyl ether; methanol / 1 h / Ambient temperature3: 71.4 percent / AcOK, H2 / 5percent Pd/C / methanol / Ambient temperature4: 63 percent / N,N-dicyclohexylcarbodimide / dioxane / 4 h / Ambient temperature  

With  dicyclohexyl-carbodiimide in  1,4-dioxane 4 h;  Ambient temperature;   

With  sodium hydroxide in  methanol; acetonitrile 0.5 h;  Ambient temperature;