N-甲基哌嗪合成路线

参考文献

Martin, Matthew W.; Newcomb, John; Nunes, Joseph J.; Boucher, Christina; Chai, Lilly; Epstein, Linda F.; Faust, Theodore; Flores, Sylvia; Gallant, Paul; Gore, Anu; Gu, Yan; Hsieh, Faye; Huang, Xin; Kim, Joseph L.; Middleton, Scot; Morgenstern, Kurt; Oliveira-dos-Santos, Antonio; Patel, Vinod F.; Powers, David; Rose, Paul; Tudor, Yanyan; Turci, Susan M.; Welcher, Andrew A.; Zack, Debra; Zhao, Huilin; Zhu, Li; Zhu, Xiaotian; Ghiron, Chiara; Ermann, Monika; Johnston, David; Saluste, Carl-Gustaf Pierre
Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1637 - 1648

109-01-3N-甲基哌嗪+

3958-57-43-硝基溴苄

198281-54-81-甲基-4-(3-硝基苯)哌嗪

参考文献

AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara
Patent: WO2012/59932 A1, 2012 ;
Location in patent: Page/Page column 139 ;
WO 2012/059932 A1

109-01-3N-甲基哌嗪+

619-23-8间硝基氯化苄

198281-54-81-甲基-4-(3-硝基苯)哌嗪

参考文献

Guagnano, Vito; Furet, Pascal; Spanka, Carsten; Bordas, Vincent; Le Douget, Mickael; Stamm, Christelle; Brueggen, Josef; Jensen, Michael R.; Schnell, Christian; Schmid, Herbert; Wartmann, Markus; Berghausen, Joerg; Drueckes, Peter; Zimmerlin, Alfred; Bussiere, Dirksen; Murray, Jeremy; Graus Porta, Diana
Journal of Medicinal Chemistry, 2011 , vol. 54, # 20 p. 7066 - 7083

109-01-3N-甲基哌嗪+

99-61-6间硝基苯甲醛

198281-54-81-甲基-4-(3-硝基苯)哌嗪

参考文献

Koroleva; Gusak; Ermolinskaya; Ignatovich
Russian Journal of Organic Chemistry, 2013 , vol. 49, # 4 p. 563 - 567
Zh. Org. Khim., 2013 , vol. 49, # 4 p. 580 - 584

109-01-3N-甲基哌嗪+

49656-04-4

20503-88-21-(4,5-二苯基-2-恶唑基)-4-甲基-哌嗪

参考文献

Marchetti; Mattalia; Rosnati
Journal of medicinal chemistry, 1968 , vol. 11, # 5 p. 1092 - 1093

109-01-3N-甲基哌嗪

19178-73-5

参考文献

Zaugg et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 2763,2764

109-01-3N-甲基哌嗪+

50-00-0甲醛+

57-41-0苯妥英

21598-58-33-[(4-甲基哌嗪-1-基)甲基]-5,5-二(苯基)咪唑烷-2,4-二酮

参考文献

Bapna, Mayank; Parashar, Bharat; Sharma, Vinod K.; Chouhan, Lalit S.
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1098 - 1106

109-01-3N-甲基哌嗪+

52334-81-32-氯-5-三氟甲基吡啶

192564-53-72-(4-甲基哌嗪)-5-三氟甲基吡啶

参考文献

Toma, Gabriel; Fujita, Ken-Ichi; Yamaguchi, Ryohei
European Journal of Organic Chemistry, 2009 , # 27 p. 4586 - 4588

109-01-3N-甲基哌嗪+

79-44-7

21579-89-5

参考文献

El-Faham, Ayman; Albericio, Fernando
Journal of Organic Chemistry, 2008 , vol. 73, # 7 p. 2731 - 2737

参考文献

Harapanhalli; McLaughlin; Howell; Rao; Adelstein; Kassis
Journal of medicinal chemistry, 1996 , vol. 39, # 24 p. 4804 - 4809