N-甲基哌嗪合成路线

参考文献

Roth, Gerald J.; Heckel, Armin; Colbatzky, Florian; Handschuh, Sandra; Kley, Joerg; Lehmann-Lintz, Thorsten; Lotz, Ralf; Tontsch-Grunt, Ulrike; Walter, Rainer; Hilberg, Frank
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4466 - 4480

109-01-3N-甲基哌嗪+

2653-16-92-氯-N-甲基-N-(4-硝基苯基)乙酰胺

1139453-98-7N,4-二甲基-N-(4-硝基苯基)-1-哌嗪乙酰胺

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/71523 A1, 2009 ;
Location in patent: Page/Page column 4; 23-24 ;

109-01-3N-甲基哌嗪+

1025916-29-3

116904-25-7

参考文献

Chemical and Pharmaceutical Bulletin, , vol. 42, # 6 p. 1279 - 1285

109-01-3N-甲基哌嗪+

113118-81-35-溴吡啶-3-甲醛

1160924-36-6

参考文献

GLAXO GROUP LIMITED; ALDER, Catherine, Mary; BALDWIN, Ian, Robert; BARTON, Nicholas, Paul; CAMPBELL, Amanda, Jennifer; CHAMPIGNY, Aurelie, Cecile; HARLING, John, David; MAXWELL, Aoife, Caitriona; SIMPSON, Juliet, Kay; SMITH, Ian, Edward, David; TAME, Christopher, John; WILSON, Caroline; WOOLVEN, James, Michael
Patent: WO2010/106016 A1, 2010 ;
Location in patent: Page/Page column 119 ;
WO 2010/106016 A1

109-01-3N-甲基哌嗪+

625-92-33,5-二溴吡啶

1130759-48-61-(5-溴吡啶-3-基)-4-甲基哌嗪

参考文献

SAMUMED, LLC; HOOD, John; KC, Sunil Kumar
Patent: WO2013/40215 A1, 2013 ;
Location in patent: Paragraph 00261 ;

109-01-3N-甲基哌嗪

116818-74-7

参考文献

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 748 - 751

109-01-3N-甲基哌嗪+

59101-37-0

116818-74-7

参考文献

Journal of Organic Chemistry, , vol. 13, p. 144,149

109-01-3N-甲基哌嗪

124673-62-7

参考文献

Wrzeciono; Linkowska; Majewska; Gzella; Stochla
Die Pharmazie, 1993 , vol. 48, # 8 p. 582 - 584

109-01-3N-甲基哌嗪

116818-76-9

参考文献

Sharma, Satyavan; Agarwal, V. K.; Dubey, S. K.; Iyer, R. N.; Anand, Nitya; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 748 - 751

109-01-3N-甲基哌嗪+

115841-54-8

115841-55-9

参考文献

Augeri; Fray; Kleinman
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 5 p. 1509 - 1511