1: 1-Bromo-2-aminobenzene With palladium diacetate; triethylamine; 4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 2-dicyclohexylphosphino-1,1'-biphenyl in 1,4-dioxane T=80°C; 1 h; 2: 2-bromo-pyridine With Ba(OH)2*8H2O in 1,4-dioxane; water T=100°C; 4 h;
参考文献
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Patent: WO2009/100014 A1, 2009 ;
Location in patent: Page/Page column 236-237 ;
1: 2-bromo-pyridine With isopropylmagnesium chloride in tetrahydrofuran T=30°C; 3.5 h; 2: With zinc(II) chloride in tetrahydrofuran T=20°C; 1.66667 h; 3: 2-iodo aniline With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 24 h; Reflux;
参考文献
Muntaner, Jaime G.; Casarrubios, Luis; Sierra, Miguel A.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 2 p. 286 - 297
