1: n-butyllithium With indium(III) chloride in tetrahydrofuran; hexane
T=-78 - 20°C; 1 h;
2: carbon monoxide; 1-(iodo)-4-methylbenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane
T=60°C; 0.5 h;
参考文献
Lee, Sung Wook; Lee, Kooyeon; Seomoon, Dong; Kim, Sundae; Kim, Hyunseok; Kim, Hyun; Shim, Eunkyong; Lee, Miae; Lee, Seokju; Kim, Misook; Lee, Phil Ho
Journal of Organic Chemistry, 2004 , vol. 69, # 14 p. 4852 - 4855
1: n-butyllithium With zinc(II) chloride in tetrahydrofuran; hexane
T=0°C; transmetallation; 0.25 h;
2: 4-methyl-2-iodophenyl triflate in tetrahydrofuran; hexane
T=-85°C; Metallation; alkylation; 0.5 h;
3: With hydrogenchloride in tetrahydrofuran; hexane
Hydrolysis; Title compound not separated from byproducts;
参考文献
Harada, Toshiro; Chiba, Minako; Oku, Akira
Journal of Organic Chemistry, 1999 , vol. 64, # 22 p. 8210 - 8213
carbon monoxide in tetrahydrofuran; diethyl ether; pentane
T=-110°C; 2 h;
参考文献
Seyferth, Dietmar; Weinstein, Robert M.; Hui, Richard C.; Wang, Wei-Liang; Archer, Colin M.
Journal of Organic Chemistry, 1992 , vol. 57, # 21 p. 5620 - 5629
