N-甲基-2-羟基乙胺合成路线 （共 285 条）
反应条件
1.) water, 60 deg C, 20-30 h, pH 6-7; Multistep reaction;
参考文献
Chuiko, Alexey; Philonenko, Ludmila; Borisevich, Anatoly; Lozinsky, Miron
Phosphorus, Sulfur and Silicon and the Related Elements, 1996 , vol. 111, p. 66
参考文献
Texaco Chemical Company
Patent: US5066804 A1, 1991 ;
参考文献
Laurent,P.A.; Bearn,L.
Bulletin de la Societe Chimique de France, 1978 , vol. <II>, p. 83 - 88
参考文献
WELFIDE CORPORATION
Patent: EP1308439 A1, 2003 ;
反应条件
formaldehyd; sodium hydrogencarbonate; acetic acid in ethanol
参考文献
Nippon Shinyaku Co., Ltd.
Patent: US4927835 A1, 1990 ;
反应条件
lithium hydride in dimethyl sulfoxide T=110°C; 1.5 h;
参考文献
Deshmukh, Mahesh S.; Das, Biswajit; Jain, Nidhi
RSC Advances, 2013 , vol. 3, # 44 p. 22389 - 22396
反应条件
triethylamine in tetrahydrofuran T=60 - 70°C; 2 h; Inert atmosphere;
参考文献
Gim, Hyo Jin; Cheon, Ye-Jin; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 3057 - 3061
反应条件
in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
Beecham Group p.l.c.
Patent: US5232925 A1, 1993 ;
反应条件
in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
Beecham Group p.l.c.
Patent: US5232925 A1, 1993 ;
参考文献
Rekka, Eleni; Kourounakis, Panos
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 179 - 184
