N-甲基-2-羟基乙胺合成路线 （共 285 条）
反应条件
in benzene
5 h; Heating;
参考文献
Witek, Stanislaw; Bielawska, Alicja; Bielawski, Jacek
Polish Journal of Chemistry, 1982 , vol. 56, # 1 p. 207 - 212
反应条件
in benzene
5 h; Heating;
参考文献
Witek, Stanislaw; Bielawska, Alicja; Bielawski, Jacek
Polish Journal of Chemistry, 1982 , vol. 56, # 1 p. 207 - 212
反应条件
in benzene
5 h; Heating;
参考文献
Witek, Stanislaw; Bielawska, Alicja; Bielawski, Jacek
Polish Journal of Chemistry, 1982 , vol. 56, # 1 p. 207 - 212
反应条件
in benzene
5 h; Heating;
参考文献
Witek, Stanislaw; Bielawska, Alicja; Bielawski, Jacek
Polish Journal of Chemistry, 1982 , vol. 56, # 1 p. 207 - 212
反应条件
in N,N-dimethyl-formamide
4 h; Ambient temperature;
参考文献
Prostakov, N. S.; Shalimov, V. P.; Cordova, Halo Montenegro; Leonova, N. I.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 11 p. 773 - 775
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 11 p. 1333 - 1335
参考文献
Bergmann et al.
Recueil des Travaux Chimiques des Pays-Bas, 1952 , vol. 71, p. 237,239
Journal of the American Chemical Society, 1951 , vol. 73, p. 5662
参考文献
Zou, Yan; Yu, Shichong; Li, Renwu; Zhao, Qingjie; Li, Xiang; Wu, Maocheng; Huang, Ting; Chai, Xiaoxun; Hu, Honggang; Wu, Qiuye
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 366 - 374
反应条件
in butan-1-ol
3 h; Heating;
参考文献
Griengl, H.; Hayden, W.; Plessing, A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 333 - 336
反应条件
sodium tris(acetoxy)borohydride; acetic acid in tetrahydrofuran
T=0 - 20°C; 5 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/4959 A1, 2007 ;
Location in patent: Page/Page column 29-30 ;
WO 2007/004959 A1
反应条件
1: 2,6-dichloro-3-carboxypyridine With hydrogenchloride; oxalyl dichloride; N,N-dimethyl-formamide in 1,4-dioxane; dichloromethane
T=20°C; 2 h;
2: 2-methylamino-ethanol With triethylamine in dichloromethane
T=20°C; 20 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7040 A1, 2007 ;
Location in patent: Page/Page column 49-50 ;
WO 2007/007040 A1
