(2R,3s)-3-苯基丝氨酸合成路线 （共 18 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Guanti, Giuseppe; Banfi, Luca; Narisano, Enrica; Scolastico, Carlo
Tetrahedron, 1988 , vol. 44, # 12 p. 3671 - 3684
反应条件
1: 70 percent / NH4Cl, NaBH4 / ethanol; H2O / 0.5 h 2: 91 percent / KOH / methanol; H2O / Ambient temperature 3: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
1: NaBH4, NH4Cl / ethanol; H2O 2: 76 percent / trifluoroacetic acid / 0 °C 3: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
1: 1.) diisopropylamine, n-BuLi / 1.) THF, 0 deg C, n-hexane, 20 min, 2.) -60 deg C, THF, 10 min, 3.) 30 min, -60 deg C 2: 76 percent / trifluoroacetic acid / 0 °C 3: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
1: 1.) diisopropylamine, n-BuLi / 1.) THF, 0 deg C, n-hexane, 20 min, 2.) -60 deg C, THF, 10 min, 3.) 5 min, -60 deg C, THF 2: NaBH4, NH4Cl / ethanol; H2O 3: 76 percent / trifluoroacetic acid / 0 °C 4: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
1: 91 percent / KOH / methanol; H2O / Ambient temperature 2: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
1: 76 percent / trifluoroacetic acid / 0 °C 2: 94 percent / H2 / 10percent Pd on carbon / aq. ethanol View Scheme
参考文献
Tetrahedron, , vol. 44, # 12 p. 3671 - 3684
反应条件
sodium hydroxide T=0 - 20°C; 1.5 h;
参考文献
Shiraiwa, Tadashi; Saijoh, Reiichi; Suzuki, Masahiro; Yoshida, Kyosuke; Nishimura, Satoshi; Nagasawa, Hisashi
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 12 p. 1363 - 1367
参考文献
Journal of the American Chemical Society, , vol. 74, p. 5459
反应条件
1: SOCl2 / 0 °C 2: aqueous HCl View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 5459
