1: 80 percent / tetrabutylammonium fluoride / tetrahydrofuran / 24 h / 25 °C 2: 88 percent / lithium, liquid NH3 / 2-methyl-propan-2-ol; tetrahydrofuran / 0.25 h / -78 °C 3: 57 percent / O2, sodium bicarbonate / Pt / acetone; H2O / 2 h / 57 °C View Scheme

Multi-step reaction with 3 steps 1: 85 percent / dimethylboron bromide / CH2Cl2 / 1 h / -78 °C2: 98 percent3: 95 percent / tetrahydrofuran / 0.25 h / -78 °C / -50 deg C, 10 min  

Multi-step reaction with 2 steps 1: 98 percent2: 95 percent / tetrahydrofuran / 0.25 h / -78 °C / -50 deg C, 10 min  

With  tetrabutyl ammonium fluoride in  tetrahydrofuran T=25°C; 24 h;