3-[(苯基甲基)氨基]戊烷二酸二甲酯合成路线 （共 2 条）
反应条件
hydrogen; palladium dihydroxide in methanol
T=20°C; 12 h;
参考文献
Bercot, Eric A.; Rovis, Tomislav
Journal of the American Chemical Society, 2005 , vol. 127, # 1 p. 247 - 254
反应条件
1: 98 percent / H2 / Pd(OH)2/C / methanol / 12 h / 20 °C
2: 93 percent / Et3N; 4-(dimethylamino)pyridine / CH2Cl2 / 1.75 h / 0 - 20 °C
3: 91 percent / aq. LiOH / tetrahydrofuran / 15 h / 20 °C
4: 98 percent / trifluoroacetic anhydride / CH2Cl2 / 3 h / 0 - 20 °C
View Scheme
参考文献
Bercot, Eric A.; Rovis, Tomislav
Journal of the American Chemical Society, 2005 , vol. 127, # 1 p. 247 - 254
