N-Boc-4-羟基哌啶合成路线

207798-38-74-(4-甲酰基苯氧基)哌啶-1-羧酸叔丁酯

参考文献

Ma, Liang; Xie, Caifeng; Ran, Yan; Liang, Xiaolin; Huang, Li; Pei, Heying; Chen, Jinying; Liu, Juan; Sang, Yun; Lai, Huijun; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 9958 - 9972

106-53-64-溴苯硫酚+

109384-19-2N-Boc-4-羟基哌啶

188527-03-9N-BOC 4-(4-溴苯基硫代)哌啶

参考文献

Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

369-34-63,4-二氟硝基苯+

109384-19-2N-Boc-4-羟基哌啶

250371-88-14-(2-氟-4-硝基苯氧基)哌啶-1-羧酸叔丁酯

参考文献

Weidner-Wells, Michele A.; Boggs, Christine M.; Foleno, Barbara D.; Melton, John; Bush, Karen; Goldschmidt, Raul M.; Hlasta, Dennis J.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 7 p. 2345 - 2351

403-19-02-氟-4-硝基苯酚+

109384-19-2N-Boc-4-羟基哌啶

250371-88-14-(2-氟-4-硝基苯氧基)哌啶-1-羧酸叔丁酯

参考文献

Noguchi, Tetsuji; Tanaka, Naoki; Nishimata, Toyoki; Goto, Riki; Hayakawa, Miho; Sugidachi, Atsuhiro; Ogawa, Taketoshi; Asai, Fumitoshi; Fujimoto, Koichi
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 6 p. 758 - 770

109384-19-2N-Boc-4-羟基哌啶

285995-13-34-(苯基磺酰基)哌啶

参考文献

Fletcher, Stephen R.; Burkamp, Frank; Blurton, Peter; Cheng, Susan K. F.; Clarkson, Robert; O'Connor, Desmond; Spinks, Daniel; Tudge, Matthew; Van Niel, Monique B.; Patel, Smita; Chapman, Kerry; Marwood, Rose; Shepheard, Sara; Bentley, Graham; Cook, Gina P.; Bristow, Linda J.; Castro, Jose L.; Hutson, Peter H.; MacLeod, Angus M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 2 p. 492 - 503

116350-38-06-羟基-1H-吲哚-2-甲酸甲酯+

109384-19-2N-Boc-4-羟基哌啶

287389-12-26-(1-boc-哌啶-4-基氧基)吲哚-2-羧酸甲酯

参考文献

Arnaiz, Damian O.; Zhao, Zuchun; Liang, Amy; Trinh, Lan; Whitlow, Marc; Koovakkat, Sunil K.; Shaw, Kenneth J.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 9 p. 957 - 961

402-44-84-氟三氟甲苯+

109384-19-2N-Boc-4-羟基哌啶

287952-08-34-[4-(三氟甲基)苯氧基]-1-哌啶羧酸 1,1-二甲基乙酯

参考文献

E. Barta, Thomas; P. Becker, Daniel; J. Bedell, Louis; A. De Crescenzo, Gary; J. McDonald, Joseph; E. Munie, Grace; Rao, Shashi; Shieh, Huey-Sheng; Stegeman, Roderick; M. Stevens, Anna; I. Villamil, Clara
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2815 - 2817

109384-19-2N-Boc-4-羟基哌啶+

213596-33-9

302924-67-0

参考文献

Berini, Christophe; Navarro, Oscar
Chemical Communications, 2012 , vol. 48, # 10 p. 1538 - 1540

828-27-3对三氟甲氧基苯酚+

109384-19-2N-Boc-4-羟基哌啶

287952-66-34-(4-(三氟甲氧基)苯氧基)哌啶-1-羧酸叔丁酯

参考文献

Shanghai Sun-Sail Pharmaceutical Science and Technology Co., Ltd; WANG, Tiancai; XIN, Ting; FAN, Houxing; CHEN, Yilang
Patent: EP2573090 A1, 2013 ;
Location in patent: Paragraph 0050-0052 ;

352-67-04-三氟甲氧基氟苯+

109384-19-2N-Boc-4-羟基哌啶

287952-66-34-(4-(三氟甲氧基)苯氧基)哌啶-1-羧酸叔丁酯

参考文献

E. Barta, Thomas; P. Becker, Daniel; J. Bedell, Louis; A. De Crescenzo, Gary; J. McDonald, Joseph; E. Munie, Grace; Rao, Shashi; Shieh, Huey-Sheng; Stegeman, Roderick; M. Stevens, Anna; I. Villamil, Clara
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2815 - 2817