1-异氰基-2-甲氧基-2-甲基丙烷合成路线 (共 5 条)
反应条件
triethylamine; trichlorophosphate in dichloromethane T=-5 - 3°C; Product distribution / selectivity;
参考文献
DRAXIS Specialty Pharmaceuticals Inc.
Patent: US2008/102028 A1, 2008 ;
Location in patent: Page/Page column 9; 11-12 ;
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane; chloroform
参考文献
Institute of Nuclear Energy Research
Patent: US5210270 A1, 1993 ;
反应条件
formamide; triethylamine in dichloromethane; water
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4988827 A1, 1991 ;
反应条件
sodium hydrogencarbonate; triethylamine in dichloromethane; water
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4864051 A1, 1989 ;
反应条件
1: Heating 2: triethylamine; phosphorus oxychloride / CH2Cl2 / Heating View Scheme
参考文献
Hao, Guiyang; Zang, Jianying; Liu, Boli
Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 1 p. 13 - 18