2-硝基-4-三氟甲基苯甲醛合成路线 （共 8 条）
反应条件
triphenylphosphine in acetone
反应条件
diisobutylaluminium hydride in benzene T=25°C; 2 h;
参考文献
Lewandowska, Elzbieta; Kinastowski, Stefan; Wnuk, Stanislaw F.
Canadian Journal of Chemistry, 2002 , vol. 80, # 2 p. 192 - 199
反应条件
hydrogenchloride Heating; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1774 - 1779
反应条件
1: 1.) NaNO2, conc. aq. HCl / 1.) H2O, 30 min, 2.) H2O, 1.5 h 2: aq. HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1774 - 1779
反应条件
ammonium hydroxide; iron(II) sulfate in ethanol T=70°C;
参考文献
Wani; Nicholas; Manikumar; Wall
Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1774 - 1779
反应条件
1: hydroxylamine hydrochloride / dimethyl sulfoxide / 90 °C 2: hydroxylamine hydrochloride; dimethyl sulfoxide / 90 °C View Scheme
参考文献
Augustine, John Kallikat; Bombrun, Agnes; Atta, Rajendra Nath
Synlett, 2011 , # 15 art. no. D12411ST, p. 2223 - 2227
反应条件
SnCl2·2H2O in ethanol
T=90°C; reductive Friedlander reaction; 4 h; Inert atmosphere;
参考文献
Venkatesan, Hariharan; Hocutt, Frances M.; Jones, Todd K.; Rabinowitz, Michael H.
Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3488 - 3491
反应条件
SnCl2·2H2O in ethanol
T=90°C; reductive Friedlander reaction; 4 h; Inert atmosphere;
参考文献
Venkatesan, Hariharan; Hocutt, Frances M.; Jones, Todd K.; Rabinowitz, Michael H.
Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3488 - 3491
