(S)-2-氮杂双环[2.2.2]辛烷-3-羧酸合成路线 (共 2 条)
反应条件
sodium hydroxide in methanol 24 h; Heating; Yield given. Yields of byproduct given;
参考文献
Vincent, Michel; Pascard, Claudine; Cesario, Michele; Remond, Georges; Bouchet, Jean-Paul; et al.
Tetrahedron Letters, 1992 , vol. 33, # 48 p. 7369 - 7372
反应条件
methanol in hexane; benzene
T=0 - 25°C; 2 h;
参考文献
ANADYS PHARMACEUTICALS, INC.
Patent: WO2008/73987 A1, 2008 ;
Location in patent: Page/Page column 85-86 ;