4-乙酰苯基三氟甲烷磺酸酯合成路线 （共 140 条）
反应条件
palladium diacetate in ethanol
T=95°C; 0.25 h; microwave irradiation;
参考文献
Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6887 - 6889
反应条件
potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine in acetonitrile
T=20°C; Suzuki cross-coupling; 48 h; Inert atmosphere;
参考文献
Proutiere, Fabien; Schoenebeck, Franziska
Angewandte Chemie - International Edition, 2011 , vol. 50, # 35 p. 8192 - 8195
反应条件
[Cu(Phen)(PPh3)2]NO3; potassium tert-butylate; palladium diacetate in 1-methyl-pyrrolidin-2-one
T=170°C; 1 h; SonicationContinuous flow reactor;
参考文献
Lange, Paul P.; Goossen, Lukas J.; Podmore, Philip; Underwood, Toby; Sciammetta, Nunzio
Chemical Communications, 2011 , vol. 47, # 12 p. 3628 - 3630
反应条件
copper(I) oxide; 1,10-phenanthroline; tris(4-methylphenyl)-phosphine; PdI2 in 1-methyl-pyrrolidin-2-one
T=170°C; 1 h; Inert atmosphere;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.
Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9336 - 9349
反应条件
1: 92 percent Chromat. / 1,1'-bis(diphenylphosphino)ferrocene, KOAc / PdCl2(dppf) / dioxane / 6 h / 80 °C
2: 93 percent / KOAc / PdCl2(dppf) / dioxane / 16 h / 80 °C
View Scheme
参考文献
Ishiyama, Tatsuo; Itoh, Yoshiya; Kitano, Takahiro; Miyaura, Norio
Tetrahedron Letters, 1997 , vol. 38, # 19 p. 3447 - 3450
反应条件
manganese; water; trifluoroacetic acid; Co(2,2'-bipyridine)Br2; lithium bromide in pyridine; N,N-dimethyl-formamide
T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne; Perichon, Jacques
Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 6130 - 6134
反应条件
1: 60 percent / Pd(PPh3)4 / tetrahydrofuran; benzene / 4 h / Heating
2: 50 percent / TBAF / tetrahydrofuran / 0 °C
View Scheme
参考文献
Arnould, Jean Claude; Didelot, Myriam; Cadilhac, Caroline; Pasquet, Marie Jeanne
Tetrahedron Letters, 1996 , vol. 37, # 26 p. 4523 - 4524
反应条件
potassium carbonate in ethanol; water
T=60°C; Suzuki-Miyaura reaction; 2 h; in air;
参考文献
Hagiwara, Hisahiro; Sasaki, Hirokazu; Tsubokawa, Norio; Hoshi, Takashi; Suzuki, Toshio; Tsuda, Tetsuya; Kuwabata, Susumu
Synlett, 2010 , # 13 p. 1990 - 1996
反应条件
1: methoxybenzene With N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in tetrahydrofuran; cyclohexane
T=-78°C; 2 h;
2: With indium(III) chloride in tetrahydrofuran; cyclohexane
T=-78 - 20°C;
3: 4-acetylphenyl triflate With bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; cyclohexane
Heating;
参考文献
Pena, Miguel A.; Sestelo, Jose Perez; Sarandeses, Luis A.
Journal of Organic Chemistry, 2007 , vol. 72, # 4 p. 1271 - 1275
反应条件
triphenyl-arsane; lithium chloride; tris-(dibenzylideneacetone)dipalladium(0) in various solvent(s)
T=80°C; 70 h;
参考文献
Farina, Vittorio; Krishnan, Bala; Marshall, Daniel R.; Roth, Gregory P.
Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5434 - 5444
