1: Et3N / Pd(PPh3)2Cl2; CuI 2: TBAF / tetrahydrofuran View Scheme

1: With 1,1'-bis-(diphenylphosphino)ferrocene; [Ni0(1,5-cyclooctadiene)2]; sodium t-butanolate in toluene T=20 - 105°C; Inert atmosphereCombinatorial reaction / High throughput screening (HTS); 2: With potassium tert-butylate in toluene T=20 - 120°C; Inert atmosphereCombinatorial reaction / High throughput screening (HTS);

copper diacetate; potassium ethylxanthate; (R)-(+)-1,1'-binaphthyl-2,2'-diamine in N,N-dimethyl-formamide T=80°C; 35 h; Inert atmosphere; Reagent/catalystTemperatureTime;