乙氧甲酰基亚甲基三苯基膦合成路线 （共 578 条）
反应条件
sodium acetate; pyridinium chlorochromate in dichloromethane
oxidation-Wittig reaction; 4 h;
参考文献
Shet, Jyoti; Desai, Vidya; Tilve, Santosh
Synthesis, 2004 , # 11 p. 1859 - 1863
参考文献
Shekhar, Vanam; Reddy, Dorigondla Kumar; Venkateswarlu, Yenamandra
Helvetica Chimica Acta, 2012 , vol. 95, # 9 p. 1593 - 1599
反应条件
T=100°C; Wittig olefination; 0.166667 h; Title compound not separated from byproducts.;
参考文献
Thiemann, Thies; Watanabe, Masataka; Tanaka, Yasuko; Mataka, Shuntaro
New Journal of Chemistry, 2004 , vol. 28, # 5 p. 578 - 584
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
Montmorillonite KSF
T=180°C; 6 h;
参考文献
Ramesh; Das, Anoop T.; Mohandass; Nagasathya
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 9 p. 1447 - 1450
反应条件
in toluene
6 h; Heating; Further byproducts given;
参考文献
Nicolaides, D. N.; Fylaktakidou, K. C.; Bezergiannidou-Balouktsi, C.; Litinas, K. E.
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 1 p. 173 - 176
反应条件
in toluene
16 h; Heating;
参考文献
Balu, N.; Thomas, Jacob V.; Bhat, Sujata V.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2821 - 2823
反应条件
1: ethyl (triphenylphosphoranylidene)acetate; propyl halide in chloroform
RefluxInert atmosphere;
2: With triethylamine in dichloromethane
T=20°C; 1 h; Inert atmosphere;
3: acetyl chloride in dichloromethane
T=20°C; Inert atmosphere;
参考文献
Na, Risong; Jing, Chengfeng; Xu, Qihai; Jiang, Hui; Wu, Xi; Shi, Jiayan; Zhong, Jiangchun; Wang, Min; Benitez, Diego; Tkatchouk, Ekaterina; Goddard, William A.; Guo, Hongchao; Kwon, Ohyun
Journal of the American Chemical Society, 2011 , vol. 133, # 34 p. 13337 - 13348
反应条件
in tetrahydrofuran; dichloromethane
T=20°C; Horner-Wadsworth-Emmons olefination; 4 h;
参考文献
Fumeaux, Rene; Menozzi-Smarrito, Candice; Stalmach, Angelique; Munari, Caroline; Kraehenbuehl, Karin; Steiling, Heike; Crozier, Alan; Williamson, Gary; Barron, Denis
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5199 - 5211
反应条件
in tetrahydrofuran
T=20 - 65°C;
参考文献
REPLIGEN CORPORATION; JACQUES, Vincent; RUSCHE, James R.; PEET, Norton P.; SINGH, Jasbir
Patent: WO2012/118782 A1, 2012 ;
Location in patent: Page/Page column 60 ;
WO 2012/118782 A1
