4-氨基苯基-N-甲基甲烷磺酰胺合成路线 (共 4 条)
反应条件
hydrogen; palladium on activated charcoal
参考文献
Heterocycles, , vol. 53, # 3 p. 665 - 673
反应条件
1: With hydrogenchloride; sodium nitrite in water T=-5 - 0°C; 0.75 h; Saturated solution; 2: With sodium sulfite in water T=0 - 65°C; 17.25 h;
参考文献
RESPIVERT LIMITED; MURRAY, Peter, John; ONIONS, Stuart, Thomas; WILLIAMS, Jonathan, Gareth; JOLY, Kevin
Patent: WO2011/158044 A2, 2011 ;
Location in patent: Page/Page column 38-39 ;
WO 2011/158044 A2
反应条件
iodine cloride in hexane; ethyl acetate; acetonitrile
参考文献
Fabre-Kramer Pharmaceuticals, Inc.
Patent: US2009/281114 A1, 2009 ;
US 20090281114 A1
反应条件
iodine cloride; calcium carbonate in methanol 16 h; Ambient temperature;
参考文献
Sternfeld, Francine; Guiblin, Alexander R.; Jelley, Richard A.; Matassa, Victor G.; Reeve, Austin J.; Hunt, Peter A.; Beer, Margaret S.; Heald, Anne; Stanton, Josephine A.; Sohal, Bindi; Watt, Alan P.; Street, Leslie J.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 677 - 690