2-(4-氯苯基)-1,1-联苯基乙醇合成路线 （共 4 条）
反应条件
1: p-bromomethylchlorobenzene With iodine; magnesium in diethyl ether T=20°C; 3 h; Inert atmosphere; 2: benzophenone in diethyl ether T=20°C; Grignard reaction; 24 h; Inert atmosphere; 3: With ammonium chloride in diethyl ether; water Saturated solution;
参考文献
Abualhasan, Murad N.; Good, James A.D.; Wittayanarakul, Kitiyaporn; Anthony, Nahoum G.; Berretta, Giacomo; Rath, Oliver; Kozielski, Frank; Sutcliffe, Oliver B.; MacKay, Simon P.
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 483 - 498
反应条件
diethyl ether; benzene
参考文献
Kharasch; Weinhouse
Journal of Organic Chemistry, 1936 , vol. 1, p. 209,227
Full Text Show Details
Tadros; Farahat; Robson
Journal of the Chemical Society, 1949 , p. 439
反应条件
sulfuric acid
Erhitzen unter vermindertem Druck;
参考文献
Miller,L.L.; Kaufman,D.A.
Journal of the American Chemical Society, 1968 , vol. 90, p. 7282 - 7287
反应条件
1: aqueous H2SO4 / Erhitzen unter vermindertem Druck
2: glacial acetic acid; bromine
View Scheme
参考文献
Miller,L.L.; Kaufman,D.A.
Journal of the American Chemical Society, 1968 , vol. 90, p. 7282 - 7287
