反应条件
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.17 h / 20 °C / |Inert atmosphere
1.2: 0 - 20 °C / |Inert atmosphere
2.1: mineral oil; N,N-dimethyl-formamide / 1 h / 0 - 20 °C / |Inert atmosphere
3.1: potassium hydroxide / toluene; methanol / 2 h / |Inert atmosphere; |Reflux
4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / |Inert atmosphere
5.1: triethylamine / dichloromethane / 14 h / |Inert atmosphere
View Scheme
参考文献
Banister, Samuel D.; Wilkinson, Shane M.; Longworth, Mitchell; Stuart, Jordyn; Apetz, Nadine; English, Katrina; Brooker, Lance; Goebel, Catrin; Hibbs, David E.; Glass, Michelle; Connor, Mark; McGregor, Iain S.; Kassiou, Michael
ACS Chemical Neuroscience, 2013 , vol. 4, # 7 p. 1081 - 1092