哌嗪合成路线 - 魔法化学

参考文献

Ley, Steven V.; Bolli, Martin H.; Hinzen, Berthold; Gervois, Anne-Geraldine; Hall, Beverley J.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 15 p. 2239 - 2241

110-85-0哌嗪+

22536-63-62-氯-4-甲氧基嘧啶

55745-88-54-甲氧基-2-(1-哌嗪基)嘧啶

参考文献

Mitsubishi Pharma Corporation
Patent: US6455528 B1, 2002 ;

110-85-0哌嗪+

777-37-72-氯-5-硝基三氟甲苯

381242-61-11-(4-硝基-2-三氟甲基苯基)-哌嗪

参考文献

European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 3167 - 3176

110-85-0哌嗪+

106-39-84-溴氯苯

38212-33-81-(4-氯苯基)哌嗪

参考文献

PROTEOSTASIS THERAPEUTICS, INC.
Patent: US2012/316193 A1, 2012 ;
Location in patent: Page/Page column 50 ;

110-85-0哌嗪+

106-46-7对二氯苯

38212-33-81-(4-氯苯基)哌嗪+

3367-54-2

参考文献

Brenner, Eric; Schneider, Raphael; Fort, Yves
Tetrahedron, 2002 , vol. 58, # 34 p. 6913 - 6924

110-85-0哌嗪+

6959-47-32-氯甲基吡啶盐酸盐

55579-01-61-[(2-吡啶基)甲基]哌嗪

参考文献

KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CHEMON INC.
Patent: WO2008/153325 A1, 2008 ;
Location in patent: Page/Page column 76 ;

110-85-0哌嗪+

4377-33-72-氯甲基吡啶

55579-01-61-[(2-吡啶基)甲基]哌嗪

参考文献

Ratilaincn, Jari; Airola, Karri; Kolehmaincn, Erkki; Rissanen, Kari
Chemische Berichte, 1997 , vol. 130, # 9 p. 1353 - 1359
Title/Abstract Full Text View citing articles Show Details
Loukiala, Satumari; Ratilainen, Jari; Airola, Karri; Valkonen, Jussi; Rissanen, Kari
Acta Chemica Scandinavica, 1998 , vol. 52, # 5 p. 593 - 602

110-85-0哌嗪

538-32-9苄脲

参考文献

Vertex Pharmaceuticals Incorporated
Patent: US5945413 A1, 1999 ;

110-85-0哌嗪+

615-20-32-氯苯并噻唑

55745-83-02-哌嗪-1-基-1,3-苯并噻唑

参考文献

KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; CHEMON INC.
Patent: WO2008/153325 A1, 2008 ;
Location in patent: Page/Page column 25-26 ;

110-85-0哌嗪+

615-20-32-氯苯并噻唑

446845-16-5+

55745-83-02-哌嗪-1-基-1,3-苯并噻唑

参考文献

Verma, Sanjeev K.; Acharya; Kaushik
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 5 p. 1324 - 1327