1: With sodium methylate in tetrahydrofuran; methanol T=0 - 20°C; 4 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; methanol; water T=20°C; Inert atmosphere;

1.1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 6 h / Inert atmosphere; Reflux 2.1: sodium methylate / tetrahydrofuran; methanol / 4 h / 0 - 20 °C / Inert atmosphere 2.2: 20 °C / Inert atmosphere View Scheme