4-碘-7H-吡咯并[2,3-d]嘧啶合成路线 （共 2 条）
反应条件
1: With hydrogen iodide in water T=20°C; 16 h; 2: With ammonia in water pH=8;
参考文献
LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCÈ VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRÍGUEZ GARRIDO, Antonio, David; CARCELLER GONZÁLEZ, Elena; SALAS SOLANA, Jordi
Patent: WO2013/37960 A1, 2013 ;
Location in patent: Page/Page column 74 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine T=100°C; P=3750.38 Torr; Inert atmosphere;
参考文献
LABORATORIOS DEL DR. ESTEVE, S.A.; DRACONIS PHARMA, S.L.; ALMIRALL, S.A.; TORRENS JOVER, Andoni; MERCÈ VIDAL, Ramon; CALDENTEY FRONTERA, Francesc Xavier; RODRÍGUEZ GARRIDO, Antonio, David; CARCELLER GONZÁLEZ, Elena; SALAS SOLANA, Jordi
Patent: WO2013/37960 A1, 2013 ;
Location in patent: Page/Page column 75 ;
