(E)4-氯-3-甲氧基-2-丁稀酸甲酯合成路线 （共 7 条）
反应条件
1: With thionyl chloride T=-10 - 20°C; 2: With methanesulfonic acid T=150°C; P=75.006 Torr;
参考文献
Salgado, Antonio; Boeykens, Mark; Gauthier, Christine; Declercq, Jean-Paul; De Kimpe, Norbert
Tetrahedron, 2002 , vol. 58, # 14 p. 2763 - 2775
反应条件
hydrogenchloride; sodium hydroxide; methanesulfonic acid; sodium chloride in thionyl chloride; dichloromethane; toluene
参考文献
Lonza Ltd.
Patent: US4966989 A1, 1990 ;
反应条件
ammonium hydroxide T=65°C; 0.5 h;
参考文献
Duc; McGarrity; Meul; Warm
Synthesis, 1992 , # 4 p. 391 - 394
反应条件
in neat (no solvent) T=200 - 205°C; 5 h;
参考文献
Duc; McGarrity; Meul; Warm
Synthesis, 1992 , # 4 p. 391 - 394
反应条件
sodium methylate in N,N-dimethyl-formamide
参考文献
Lonza Ltd.
Patent: US5087760 A1, 1992 ;
反应条件
sodium azide in acetonitrile
5 h; Heating;
参考文献
Salgado, Antonio; Boeykens, Mark; Gauthier, Christine; Declercq, Jean-Paul; De Kimpe, Norbert
Tetrahedron, 2002 , vol. 58, # 14 p. 2763 - 2775
