2-甲基-2-丙基2-羟基丁酸酯合成路线 （共 7 条）
反应条件
hydrogen; C50H44Cl2N2O8P4Ru(4-)*Zr(4+) in methanol
T=20°C; P=72402.6 Torr; 20 h; Product distribution / selectivity;
参考文献
Lin, Wenbin; Hu, Aiguo; Ngo, Helen L.
Patent: US2004/192543 A1, 2004 ;
Location in patent: Page/Page column 9 ;
反应条件
hydrogen; C50H44Cl2N2O8P4Ru(4-)*Zr(4+) in methanol
T=20°C; P=72402.6 Torr; 20 h; Product distribution / selectivity;
参考文献
Lin, Wenbin; Hu, Aiguo; Ngo, Helen L.
Patent: US2004/192543 A1, 2004 ;
Location in patent: Page/Page column 9 ;
反应条件
Pseudomonas cepacia lipase immobilized on ceramic; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl in toluene
T=25°C; 120 h;
参考文献
Choi, Jun Ho; Choi, Yoon Kyung; Kim, Yu Hwan; Park, Eun Sil; Kim, Eun Jung; Kim, Mahn-Joo; Park, Jaiwook
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1972 - 1977
反应条件
hydrogenchloride; hydrogen; [RuCl2-((R)-binap)]*NEt3 in methanol
T=40°C; P=2585.7 Torr; 8 h; effect of acid, other substrate; Kinetics;
参考文献
King, Steven A.; Thompson, Andrew S.; King, Anthony O.; Verhoeven, Thomas R.
Journal of Organic Chemistry, 1992 , vol. 57, # 25 p. 6689 - 6691
反应条件
sodium carbonate in methanol
Ambient temperature; Yield given;
参考文献
Bachmann, Beat M.; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 12 p. 2430 - 2461
反应条件
1: 78 percent / HAl(iBu)2 / tetrahydrofuran / -78 °C
2: 82 percent / Raney Nickel
View Scheme
参考文献
Solladie, Guy; Almario, Antonio
Tetrahedron Letters, 1992 , vol. 33, # 18 p. 2477 - 2480
反应条件
K-10 lipase
T=25°C; 16 h; 0.2M phosphate buffer, pH 6.9; further catalyst;
参考文献
Scilimati, A.; Ngooi, T. K.; Sih, Charles J.
Tetrahedron Letters, 1988 , vol. 29, # 39 p. 4927 - 4930
