(Sa,S)-[(C8H12)Ir(P(3,5-(tert-butyl)2C6H3)2C8H7CC8H7C3NOH3(benzyl))][tetrakis[3,5-bis(trifluoromethyl)phenyl]borate]; hydrogen; triethylamine in methanol T=60°C; P=4560.31 Torr; 20 h; AutoclaveInert atmosphere; enantioselective reaction;

hydrogenchloride in argon-atmosphere; hydrogen

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1.5 h / 25 - 40 °C / |Inert atmosphere; |Schlenk technique 1.2: |Cooling with ice 2.1: triethylamine; hydrogen; (Sa,S)-[(C8H12)Ir(P(3,5-(tert-butyl)2C6H3)2C8H7CC8H7C3NOH3(benzyl))][tetrakis[3,5-bis(trifluoromethyl)phenyl]borate] / methanol / 20 h / 60 °C / 4560.31 Torr / |Autoclave; |Inert atmosphere View Scheme

[Ru(OAc)2(p-cymene)]; (R)-6,6'-dimethoxy-P2,P2,P2',P2'-tetrakis-[4-(carbonyloxy)phenyl]biphenyl-2,2'-bisphosphine; hydrogen; triethylamine in methanol T=25°C; P=135014 Torr; 15 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

[Ru(OAc)2(p-cymene)]; (S)-6,6'-dimethoxy-P2,P2,P2',P2'-tetrakis-[3,5-di(carbonyloxy)phenyl]biphenyl-2,2'-bisphosphine sodium salt; hydrogen; water-d2; triethylamine T=25°C; P=135014 Torr; Inert atmosphere; Mechanism; Concentration;

1: diphenylphosphoranyl azide; triethylamine / 20 h / 100 °C 2: hydrogenchloride / water; ethyl acetate / 16 h / 20 °C / Cooling with ice View Scheme