1: 1.) TsCl, 2.) NaH / 1.) pyridine, 0 deg C, 4 d, 2.) reflux, 90 min 2: 40 percent / NH4Cl / 24 h 3: 95 percent / NaBH4 / methanol / 90 h View Scheme

sodium hydride; p-toluenesulfonyl chloride 1.) pyridine, 0 deg C, 4 d, 2.) reflux, 90 min; Yield given. Multistep reaction;

Multi-step reaction with 2 steps 1: 1.) TsCl, 2.) NaH / 1.) pyridine, 0 deg C, 4 d, 2.) reflux, 90 min2: 40 percent / NH4Cl / 24 h