1: H2 / Pd/C 2: 77 percent / diethyl phosphorocyanidate, triethylamine, molecular sieves 4A / tetrahydrofuran / 0 gradC for 1 h. then room temp. for 40 min. 4: 80 percent / H2 / palladium-carbon / ethanol View Scheme

Multi-step reaction with 2 steps 1: H2 / Pd/C2: 69 percent / diethyl phosphorocyanidate, triethylamine, molecular sieves 4A / tetrahydrofuran / 0 gradC for 1 h. then room temp. for 40 min.  

Multi-step reaction with 3 steps 1: H2 / Pd/C2: 77 percent / diethyl phosphorocyanidate, triethylamine, molecular sieves 4A / tetrahydrofuran / 0 gradC for 1 h. then room temp. for 40 min.  

Multi-step reaction with 2 steps 1: H2 / Pd/C2: 77 percent / diethyl phosphorocyanidate, triethylamine, molecular sieves 4A / tetrahydrofuran / 0 gradC for 1 h. then room temp. for 40 min.