2-(氧杂环丁-3-亚基)乙酸甲酯合成路线 （共 2 条）
反应条件
in dichloromethane T=0 - 5°C; 0.25 h;
参考文献
Gobbi, Luca; Jaeschke, Georg; Rodriguez Sarmiento, Rosa Maria; Steward, Lucinda
Patent: US2010/75983 A1, 2010 ;
Location in patent: Page/Page column 49 ;
US 20100075983 A1
反应条件
1: oxetan-3-ylidene-acetic acid methyl ester With chloro-trimethyl-silane; copper(l) iodide in tetrahydrofuran T=20°C; 0.25 h; 2: methyl-magnesium chloride in tetrahydrofuran T=-15 - 20°C; 3: With ammonium chloride in tetrahydrofuran
参考文献
Gobbi, Luca; Jaeschke, Georg; Rodriguez Sarmiento, Rosa Maria; Steward, Lucinda
Patent: US2010/75983 A1, 2010 ;
Location in patent: Page/Page column 49; 50 ;
US 20100075983 A1
