(1S-反式)-2-[(苯甲氧基)甲基]-3-环戊烯-1-醇合成路线 （共 23 条）
反应条件
1: VO(acac)2, t-BuOOH / CH2Cl2 2: NaH, Bu4NI / dimethylformamide 3: 60 percent / LiH / dimethylformamide / 2 h / 125 °C 4: 82 percent / TEA, DMAP / CH2Cl2 5: Dess-Martin reagent, t-BuOH / CH2Cl2 6: Zn, TiCl4 / tetrahydrofuran; CH2Cl2 View Scheme
参考文献
Bisacchi; Chao; Bachard; Daris; Innaimo; Jacobs; Kocy; Lapointe; Martel; Merchant; Slusarchyk; Sundeen; Young; Colonno; Zahler
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 2 p. 127 - 132
反应条件
1: VO(acac)2, t-BuOOH / CH2Cl2 2: NaH, Bu4NI / dimethylformamide 3: 60 percent / LiH / dimethylformamide / 2 h / 125 °C 4: 82 percent / TEA, DMAP / CH2Cl2 View Scheme
参考文献
Bisacchi; Chao; Bachard; Daris; Innaimo; Jacobs; Kocy; Lapointe; Martel; Merchant; Slusarchyk; Sundeen; Young; Colonno; Zahler
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 2 p. 127 - 132
反应条件
1.1: NaH / tetrahydrofuran / 1 h / 20 °C
1.2: 92 percent / tetrabutylammonium iodide / tetrahydrofuran / 12 h / 20 °C
2.1: 9-BBN / tetrahydrofuran / 12 h / 20 °C
2.2: hydroxylamine-O-sulfonic acid / tetrahydrofuran / 3 h / 70 °C
View Scheme
参考文献
Ludek, Olaf R.; Meier, Chris
Synthesis, 2003 , # 13 p. 2101 - 2109
