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结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
110674-08-3
合成路线
(共 6 条)
110674-08-3
→
反应条件
81-25-4
胆汁酸
反应条件
1: 95 percent / 65 h / 80 °C 2: 83 percent / alumina / benzene / 18 h 3: 76 percent / NaBH4, PdCl2 / methanol / 2 h / Ambient temperature 4: KOH / methanol / 1 h / Heating View Scheme
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al.
Synthesis, 1986 , # 12 p. 998 - 1004
110674-08-3
→
反应条件
81-25-4
胆汁酸
反应条件
1: 95 percent / 65 h / 80 °C 2: 83 percent / alumina / benzene / 18 h 3: 76 percent / NaBH4, PdCl2 / methanol / 2 h / Ambient temperature 4: KOH / methanol / 1 h / Heating View Scheme
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al.
Synthesis, 1986 , # 12 p. 998 - 1004
13587-11-6
(7alpha,12alpha)-7,12-二羟基-3-氧代胆-4-烯-24-酸
→
反应条件
110674-08-3
反应条件
Multi-step reaction with 6 steps 1: 1.) Li/NH3 2: 86 percent / 4-dimethylaminopyridine / benzene; pyridine / 0.08 h / Ambient temperature3: 96 percent / K2CrO4 / acetic acid; H2O / Ambient temperature4: 100 percent / KOH / methanol / 12 h / Heating5: p-toluenesulfonic acid / Ambient temperature6: 88 percent / pyridine / 24 h / Ambient temperature
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al. Synthesis, 1986 , # 12 p. 998 - 1004
110674-05-0
→
反应条件
110674-08-3
反应条件
Multi-step reaction with 3 steps 1: 100 percent / KOH / methanol / 12 h / Heating2: p-toluenesulfonic acid / Ambient temperature3: 88 percent / pyridine / 24 h / Ambient temperature
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al. Synthesis, 1986 , # 12 p. 998 - 1004
110674-04-9
→
反应条件
110674-08-3
反应条件
Multi-step reaction with 4 steps 1: 96 percent / K2CrO4 / acetic acid; H2O / Ambient temperature2: 100 percent / KOH / methanol / 12 h / Heating3: p-toluenesulfonic acid / Ambient temperature4: 88 percent / pyridine / 24 h / Ambient temperature
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al. Synthesis, 1986 , # 12 p. 998 - 1004
110674-08-3
+
68-12-2
N,N-二甲基甲酰胺
→
反应条件
110674-09-4
反应条件
T=80°C; 65 h;
参考文献
Iida, Takashi; Shinohara, Toshiyuki; Momose, Toshiaki; Tamura, Toshitake; Matsumoto, Taro; et al. Synthesis, 1986 , # 12 p. 998 - 1004