8-氨基-4-酮-2-(四氮唑-5-基)-4H-1-苯并吡喃盐酸盐合成路线 （共 5 条）
反应条件
hydrogenchloride; hydrogen; Pd-Cl in methanol
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 84 - 91
反应条件
1: NaN3, pyridinium chloride / 100 °C 2: H2, conc. HCl / Pd-Cl / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 84 - 91
反应条件
1: POCl3 / dimethylformamide 2: NaN3, pyridinium chloride / 100 °C 3: H2, conc. HCl / Pd-Cl / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 84 - 91
反应条件
1: NH3 / methanol 2: POCl3 / dimethylformamide 3: NaN3, pyridinium chloride / 100 °C 4: H2, conc. HCl / Pd-Cl / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 84 - 91
反应条件
triethylamine in isobutyramide T=0 - 25°C;
参考文献
PHARMACOSTECH CO., LTD.; KIM, Jae Won; CHA, Young Gwan; RYU, Hyung Chul; KIM, Sun Joo
Patent: WO2010/2075 A1, 2010 ;
Location in patent: Page/Page column 17-18 ;
