4-氯-2-(氯甲基)-1,3-苯并噻唑合成路线 （共 3 条）
参考文献
Kotani, Takayuki; Ishii, Akira; Nagaki, Yasuhiro; Toyomaki, Yoshio; Yago, Hisashi; Suehiro, Seishi; Okukado, Nobuhisa; Okamoto, Kaoru
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 2 p. 297 - 304
反应条件
1: NH2NH2*H2O / 24 h / Ambient temperature 2: ethanol / 2 h / 60 °C View Scheme
参考文献
Kotani, Takayuki; Ishii, Akira; Nagaki, Yasuhiro; Toyomaki, Yoshio; Yago, Hisashi; Suehiro, Seishi; Okukado, Nobuhisa; Okamoto, Kaoru
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 2 p. 297 - 304
反应条件
1: 1.) aq. NaNO2, 85percent H3PO4, 2.) 50percent H3PO2 / 1.) -10 deg C - -4 deg C, 2.) from 0 deg C to RT 2: NH2NH2*H2O / 24 h / Ambient temperature 3: ethanol / 2 h / 60 °C View Scheme
参考文献
Kotani, Takayuki; Ishii, Akira; Nagaki, Yasuhiro; Toyomaki, Yoshio; Yago, Hisashi; Suehiro, Seishi; Okukado, Nobuhisa; Okamoto, Kaoru
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 2 p. 297 - 304
