2-氯甲基噁唑并[4,5-b]吡啶合成路线 (共 5 条)
反应条件
1: in diethylene glycol dimethyl ether T=80°C; 6 h; 2: With toluene-4-sulfonic acid in diethylene glycol dimethyl ether T=80°C; 48 h;
参考文献
US2006/172995 A1, ;
Page/Page column 57 ;
反应条件
p-toluenesulfonic acid monohydrate in methanol; diethylene glycol dimethyl ether
反应条件
trichloroisocyanuric acid in 1,2-dichloro-ethane 3 h; Heating;
参考文献
Heterocycles, , vol. 41, # 3 p. 477 - 486
反应条件
in diethylene glycol dimethyl ether T=60°C; 4 h;
参考文献
Mylari, Banavara L.; Scott, Pamela J.; Zembrowski, William J.
Synthetic Communications, 1989 , vol. 19, # 16 p. 2921 - 2924
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile 20 h; Heating;
参考文献
Saari, Walfred S.; Wai, John S.; Fisher, Thorsten E.; Thomas, Craig M.; Hoffman, Jacob M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3792 - 3802