4-溴-1H-吲哚-3-羧酸合成路线 (共 4 条)
反应条件
1: With water; potassium hydroxide in ethanol T=20°C; 1.5 h; 2: With hydrogenchloride; water
参考文献
Urwyler, Stephan; Floersheim, Philipp; Roy, Bernard L.; Koller, Manuel
Journal of Medicinal Chemistry, 2009 , vol. 52, # 16 p. 5093 - 5107
反应条件
sodium chlorite; 2-methyl-but-1(2)-ene
参考文献
Yamada, Fumio; Somei, Masanori
Heterocycles, 1987 , vol. 26, # 5 p. 1173 - 1176
反应条件
1: 4-bromo-1H-indole-3-carboxylic acid With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane 1.5 h; Inert atmosphere; 2: methanol in dichloromethane T=0 - 20°C;
参考文献
Voute, Nicholas; Philp, Douglas; Slawin, Alexandra M. Z.; Westwood, Nicholas J.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 2 p. 442 - 450
反应条件
in diethyl ether Yield given;
参考文献
Yamada, Fumio; Somei, Masanori
Heterocycles, 1987 , vol. 26, # 5 p. 1173 - 1176