potassium hydroxide T=5°C; 0.5 h;

1: 1) HBF4, NaNO2 / 1) water, 0 deg C, 1 h, 2) 70 deg C, 1h 2: 96 percent / 2 N KOH / 0.5 h / 5 °C View Scheme

1: 87 percent / Fe, AcOH / H2O / 2 h / below 50 deg C 2: 1) HBF4, NaNO2 / 1) water, 0 deg C, 1 h, 2) 70 deg C, 1h 3: 96 percent / 2 N KOH / 0.5 h / 5 °C View Scheme

1: 93 percent / aq. KClO3, conc. HCl / 0.25 h / 50 - 60 °C 2: 98 percent / POCl3, quinoline / 2 h / 120 °C 3: 87 percent / Fe, AcOH / H2O / 2 h / below 50 deg C 4: 1) HBF4, NaNO2 / 1) water, 0 deg C, 1 h, 2) 70 deg C, 1h 5: 96 percent / 2 N KOH / 0.5 h / 5 °C View Scheme

1: 98 percent / POCl3, quinoline / 2 h / 120 °C 2: 87 percent / Fe, AcOH / H2O / 2 h / below 50 deg C 3: 1) HBF4, NaNO2 / 1) water, 0 deg C, 1 h, 2) 70 deg C, 1h 4: 96 percent / 2 N KOH / 0.5 h / 5 °C View Scheme

sodium hydroxide; sodium hypochlorite in water Ambient temperature; Title compound not separated from byproducts;